Ethylene Glycol Ethyl Ether CAS#110-80-5
2-Ethoxyethanol is a stable, colorless, flammable liquid that is produced synthetically worldwide. It belongs to the glycol ether solvent family and is commercially known as Ethyl Cellosolve or Cellosolve, a trademark registered by Union Carbide in 1924.
This compound was originally developed to combine the chemical properties of both alcohols and ethers, providing both hydrophilic and lipophilic characteristics while maintaining lower volatility, which contributes to improved production performance. Glycol ethers are synthesized through the reaction of anhydrous alcohols with ethylene oxide.
2-Ethoxyethanol Chemical Properties
Melting point | -100 °C |
Boiling point | 135 °C(lit.) |
density | 0.93 g/mL at 25 °C(lit.) |
vapor density | 3.1 (vs air) |
vapor pressure | 3.8 mm Hg ( 20 °C) |
refractive index | n20/D 1.407(lit.) |
Fp | 107.6 °F |
storage temp. | Store below +30°C. |
solubility | water: miscible |
pka | 14.44±0.10(Predicted) |
form | Liquid |
color | Clear, colorless |
Odor | Sweetish; mild, pleasant, ethereal. |
PH | 7 (20°C) |
Odor Threshold | 0.58ppm |
explosive limit | 1.8-15.7%(V) |
Water Solubility | miscible |
FreezingPoint | -70℃ |
Thermal Conductivity | 0.169 W/(m·K) at 25 ℃ |
λmax | λ: 215 nm Amax: 1.00 |
λ: 225 nm Amax: 0.50 | |
λ: 250 nm Amax: 0.20 | |
λ: 305 nm Amax: 0.01 | |
Merck | 143750 |
BRN | 1098271 |
Henry's Law Constant | 8.9×100 mol/(m3Pa) at 25℃, Johanson and Dynésius (1988) |
Exposure limits | TLV-TWA skin 5 ppm (18.5 mg/m3) (ACGIH). . |
Dielectric constant | 29.6（24℃） |
Stability: | Stable. Readily forms explosive mixtures with air - note the wide explosion range. Vapour may travel considerable distance to a source of ignition. Flammable. Incompatible with strong acids, strong bases, strong oxidizing agents, aluminium, alkalies. |
Cosmetics Ingredients Functions | SOLVENT |
VISCOSITY CONTROLLING | |
Cosmetic Ingredient Review (CIR) | 2-Ethoxyethanol (110-80-5) |
InChI | 1S/C4H10O2/c1-2-6-4-3-5/h5H,2-4H2,1H3 |
InChIKey | ZNQVEEAIQZEUHB-UHFFFAOYSA-N |
SMILES | CCOCCO |
LogP | 0.32 at 20℃ |
Surface tension | 28.6mN/m at 20°C |
CAS DataBase Reference | 110-80-5(CAS DataBase Reference) |
NIST Chemistry Reference | Ethanol, 2-ethoxy-(110-80-5) |
EPA Substance Registry System | 2-Ethoxyethanol (110-80-5) |
Safety Information
Hazard Codes | T |
Risk Statements | 60-61-10-20/21/22-20/22 |
Safety Statements | 53-45 |
OEB | B |
OEL | TWA: 0.5 ppm (1.8 mg/m3) [skin] |
RIDADR | UN 1171 |
WGK Germany | 1 |
RTECS | KK8050000 |
Autoignition Temperature | 460 °F |
TSCA | TSCA listed |
HazardClass | 3 |
PackingGroup | III |
HS Code | 29094990 |
Storage Class | 3 - Flammable liquids |
Hazard Classifications | Acute Tox. 3 Inhalation |
Acute Tox. 4 Oral | |
Flam. Liq. 3 | |
Repr. 1B | |
Hazardous Substances Data | 110-80-5(Hazardous Substances Data) |
Toxicity | Acute oral LD50 for guinea pigs 1,400 mg/kg, mice 2,451 mg/kg, rats 3,000 mg/kg, rabbits 3,100 mg/kg (quoted, RTECS, 1985). |
IDLA | 500 ppm |
Product Application of Ethylene Glycol Ethyl Ether CAS#110-80-5
Ethylene glycol monoethyl ether is widely used in varnish removers, lacquers, and serves as a solvent for printing inks, duplicating fluids, and epoxy materials.
Ethylene glycol monobutyl ether is applied in hydraulic fluids and functions as a coupling agent for water-based coatings. It is also used in vinyl and acrylic paints, varnishes, and as a solvent in products such as spray lacquers, enamels, dry cleaning formulations, textiles, and cosmetics.
