Cetrimonium chloride, also known as hexadecyltrimethylammonium chloride, is a white crystalline powder that dissolves readily in both isopropyl alcohol and water. When shaken, it generates abundant foam. It demonstrates excellent compatibility with cationic, nonionic, and amphoteric surfactants. The compound offers strong chemical stability, with resistance to heat, light, pressure, as well as strong acids and alkalis. In addition, it provides outstanding penetration, softening, emulsification, antistatic, biodegradable, and bactericidal properties.
N-Hexadecyltrimethylammonium chloride Chemical Properties
| Melting point | 232-234 °C |
| Boiling point | 475.54°C (rough estimate) |
| Density | 0.968 g/mL at 25 °C |
| Vapor pressure | 0.006Pa at 25℃ |
| Refractive index | n20/D 1.3778 |
| Storage temp | Store below +30°C. |
| Solubility | Water (Slightly) |
| Form | Amorphous Powder |
| Color | White |
| Specific Gravity | 0.968 |
| PH | pH(50g/l, 25℃) : 6.0～8.5 |
| Odor | at 100.00?%. bland |
| Water Solubility | Soluble |
| BRN | 3657974 |
| InChIKey | WOWHHFRSBJGXCM-UHFFFAOYSA-M |
| LogP | 3.08 at 25℃ |
| CAS DataBase Reference | 112-02-7(CAS DataBase Reference) |
| EPA Substance Registry System | Cetyl trimethyl ammonium chloride (112-02-7) |
Safety Information
| Hazard Codes | Xi,N,Xn |
| Risk Statements | 38-41-50-50/53-37/38-22-43-36/37/38 |
| Safety Statements | 26-39-60-61-37/39-36 |
| RIDADR | UN 3082 9/PG 3 |
| WGK Germany | 3 |
| RTECS | ML9145000 |
| F | 3 |
| TSCA | Yes |
| HazardClass | 8 |
| PackingGroup | III |
| HS Code | 29239000 |
| Hazardous Substances Data | 112-02-7(Hazardous Substances Data) |
| Toxicity | LD50 skin in rabbit: 4300uL/kg/24H |
Product Application of N-Hexadecyltrimethylammonium Chloride (CAS#112-02-7)
Cetrimonium chloride is a versatile cationic surfactant widely applied across multiple industries. It is used in asphalt and waterproof coating emulsification, glass fiber softening, industrial auxiliary processes, and as a silicone oil emulsifier. In the pharmaceutical sector, it serves as an auxiliary agent, while in cosmetics, it is commonly employed in hair conditioners for emulsification and conditioning. Additionally, it functions as a textile and leather auxiliary, emulsion foaming agent, fiber softener, and antistatic agent. Other applications include polyester silk processing, organic bentonite covering, protein flocculation and water treatment, as well as disinfectants for silkworm tools and general cleaning, disinfection, and sterilization.
