Product Description of Benzethonium Chloride CAS#121-54-0 Classified as a next‑generation quaternary ammonium biocide, benzethonium chloride enjoys broad adoption across home chemical and cosmetic sectors. Thanks to its potent germ‑removing and antimicrobial traits, this compound acts as a vital functional additive for numerous sanitizing and personal care mixes.
Apart from consumer goods, this substance also boasts prominent uses within the healthcare industry as a highly efficient antimicrobial constituent. In many western nations, it is commonly formulated into eye drops and injectable preparations for antibacterial purposes.
Beyond the above applications, benzethonium chloride functions as an essential synthetic precursor for heparin sodium. This feature underscores its great significance for pharmaceutical production workflows.
Benzethonium chloride Chemical Properties
| Melting point | 162-164 °C (lit.) |
| Boiling point | 162℃[at 101 325 Pa] |
| Density | 0.998 g/mL at 20 °C |
| Vapor pressure | < 0.001 hPa @ 2°C |
| Refractive index | 1.5650 (estimate) |
| Storage temp. | 2-8°C |
| Solubility | H2O: 0.1 M at 20 °C, clear, colorless |
| Form | Liquid |
| Color | White |
| PH | 5.5-7.5 (25℃, 0.1M in H2O) |
| Odor | Odorless |
| PH Range | 5.5 - 7.5 |
| Water Solubility | 1-5 g/100 mL at 18 ºC |
| Sensitive | Hygroscopic |
| Merck | 141074 |
| BRN | 3898548 |
| Stability | Stability Stable, but hygroscopic. Incompatible with strong oxidizing agents, soap, anionic detergents, nitrates, acids. Light sensitive. |
| LogP | 1.08 at 20℃ |
| CAS DataBase Reference | 121-54-0(CAS DataBase Reference) |
| EPA Substance Registry System | Benzethonium chloride (121-54-0) |
Safety Information
| Hazard Codes | Xn,N,C |
| Risk Statements | 22-37/38-41-36-36/37/38-20/21/22-50/53-34-52/53 |
| Safety Statements | 26-36/39-24/25-36/37/39-61-45 |
| RIDADR | UN1759 |
| WGK Germany | 2 |
| RTECS | BO7175000 |
| F | 8 |
| TSCA | Yes |
| HazardClass | 8 |
| PackingGroup | III |
| HS Code | 29239000 |
| Hazardous Substances Data | 121-54-0(Hazardous Substances Data) |
| Toxicity | LD50 i.v. in mice: 29.5 mg/kg (Weiss) |

Product Application of Benzethonium Chloride CAS#121-54-0 Benzethonium chloride maintains steady market demand and finds wide acceptance within pharmaceutical, household chemical and cosmetic segments.
The heparin sodium industry alone consumes over 200 tons of this substance each year. It mainly supports the purification process of heparin sodium, as well as the manufacturing of low‑molecular‑weight heparin sodium and enoxaparin.
For household chemical products, disinfecting wipes commonly incorporate benzethonium chloride as their germicidal active substance, with annual usage volume amounting to dozens of tons. Meanwhile, the personal care and sanitization market is undergoing fast growth, and its total consumption is projected to keep climbing.
This compound is also well received in cosmetic formulations and environmental disinfection scenarios. It possesses great room for popularization, covers a wide range of usage scenarios and boasts promising market outlooks.

