Isopropyl Acetate CAS#108-21-4
Isopropyl acetate is a colorless, clear, volatile liquid that bears a mild fruity fragrance. It is fully blendable with most organic solvents such as alcohols, ketones and ethers, and its solubility in water reaches roughly 2.9% by mass at 20°C.
Melting point | -73 °C |
Boiling point | 88.8 °C |
density | 0.872 g/mL at 25 °C(lit.) |
vapor density | 3.5 (vs air) |
vapor pressure | 47 mm Hg ( 20 °C) |
refractive index | n20/D 1.377(lit.) |
FEMA | 2926 | ISOPROPYL ACETATE |
Fp | 62 °F |
storage temp. | Store below +30°C. |
solubility | 1 M HCl: soluble50mg/mL, clear to slightly hazy, colorless |
form | Liquid |
color | Clear colorless |
Odor | Pleasant, fruity; nonresidual. |
Odor Threshold | 0.16ppm |
Odor Type | ethereal |
biological source | synthetic |
explosive limit | 1.8%, 37°F |
Water Solubility | 2.90 g/100 mL |
FreezingPoint | -73.4℃ |
Sensitive | Moisture Sensitive |
JECFA Number | 305 |
Merck | 145205 |
BRN | 1740761 |
Henry's Law Constant | 3.3×10-2 mol/(m3Pa) at 25℃, Brockbank (2013) |
Exposure limits | TLV-TWA 250 ppm (～950 mg/m3) (ACGIH, MSHA, and OSHA); TLV-STEL 310 ppm (～1185 mg/m3) (ACGIH); IDLH 16,000 ppm (NIOSH). |
Stability: | Stable. Flammable - note low flash point. Incompatible with strong oxidizing agents, strong acids, nitrates, alkali metals. May attack some plastics and rubber. |
Cosmetics Ingredients Functions | SOLVENT |
Cosmetic Ingredient Review (CIR) | Isopropyl acetate (108-21-4) |
InChI | 1S/C5H10O2/c1-4(2)7-5(3)6/h4H,1-3H3 |
InChIKey | JMMWKPVZQRWMSS-UHFFFAOYSA-N |
SMILES | CC(C)OC(C)=O |
LogP | 1.03-1.18 at 20℃ |
Surface tension | 21.89mN/m at 298.15K |
CAS DataBase Reference | 108-21-4(CAS DataBase Reference) |
NIST Chemistry Reference | Acetic acid, 1-methylethyl ester(108-21-4) |
EPA Substance Registry System | Isopropyl acetate (108-21-4) |
Safety Information
Hazard Codes | F,Xi |
Risk Statements | 11-36/37/38-67-66-36 |
Safety Statements | 16-26-36-33-29 |
RIDADR | UN 1220 |
WGK Germany | 1 |
RTECS | AI4930000 |
Autoignition Temperature | 894 °F |
TSCA | TSCA listed |
HazardClass | 3 |
PackingGroup | II |
HS Code | 29153900 |
Storage Class | 3 - Flammable liquids |
Hazard Classifications | Eye Irrit. 2 |
Flam. Liq. 2 | |
STOT SE 3 | |
Hazardous Substances Data | 108-21-4(Hazardous Substances Data) |
Toxicity | LD50 orally in rats: 6.75 g/kg (Smyth) |
IDLA | 1,800 ppm |
Product Application of CAS#108-21-4
Isopropyl acetate is primarily used as a solvent in coatings and printing inks. It is also widely used as an industrial dehydrating agent, an extractant in pharmaceutical manufacturing, and a fragrance ingredient in various formulations.
