Crystalline leaflets or a white crystalline powder with a bitter taste. It is soluble in 25 parts of water, slightly soluble in hot alcohol, and soluble in diluted mineral acids and alkaline solutions. It sublimes at 168–170°C and melts with decomposition at approximately 284°C. The pH of a 1% solution ranges from 5.5 to 7.0. The absolute is obtained by alcoholic extraction of the concrete with yields of about 55–60%, resulting in a semisolid, olive-green mass with a characteristic ambergris aroma.
L-Isoleucine Chemical Properties
| Melting point | 288 °C (dec.) (lit.) |
| Alpha | 41 º (c=4, 6N HCl) |
| Boiling point | 225.8±23.0 °C(Predicted) |
| Bulk density | 470kg/m3 |
| Density | 1.2930 (estimate) |
| FEMA | 4675 | L-ISOLEUCINE |
| Refractive index | 40.5 ° (C=4, 6mol/L HCl) |
| Fp | 168-170°C |
| Storage temp | Store below +30°C |
| Solubility | 1 M HCl: 50 mg/mL |
| Form | powder |
| Pka | 2.32, 9.76(at 25℃) |
| Color | White to Off-white |
| Odor | odorless |
| PH | 5.5-6.5 (40g/l, H2O, 20℃) |
| Biological source | synthetic |
| Optical Rotation | [α]20/D +41.0±1°, c = 5% in 6 M HCl |
| Water Solubility | 41.2 g/L (50 ºC) |
| λmax | λ: 260 nm Amax: 0.07 λ: 280 nm Amax: 0.05 |
| JECFA Number | 2118 |
| Merck | 14,5179 |
| Sublimation | 168-170 ºC |
| BRN | 1721792 |
| InChIKey | AGPKZVBTJJNPAG-WHFBIAKZSA-N |
| LogP | 0.80 |
| CAS DataBase Reference | 73-32-5(CAS DataBase Reference) |
| NIST Chemistry Reference | Isoleucine(73-32-5) |
| EPA Substance Registry System | L-Isoleucine (73-32-5) |
Safety Information
| Hazard Codes | Xn |
| Risk Statements | 40 |
| Safety Statements | 24/25-36-22 |
| WGK Germany | 3 |
| RTECS | NR4705000 |
| TSCA | Yes |
| HS Code | 29224995 |
| Hazardous Substances Data | 73-32-5(Hazardous Substances Data) |
| Toxicity | LD50 intraperitoneal in rat: 6822mg/kg |
L-Isoleucine, also called Isoleucine, is an amino acid and an isomer of leucine. It plays a key role in hemoglobin synthesis and in regulating blood sugar and energy levels. As an essential amino acid that cannot be synthesized by the body, L-Isoleucine supports endurance and aids in muscle repair and rebuilding. It is particularly valuable for bodybuilders, as it helps increase energy and promotes recovery after training.
