Product Description of 4‑Chloro‑3‑methylphenol CAS#59‑50‑7
4‑Chloro‑3‑methylphenol occurs as colorless crystals. Its melting point is 66°C (or 55.5°C) and boiling point is 235°C. At 20°C, 1 gram of this compound dissolves in 250 mL of water, and its solubility increases in hot water. It dissolves freely in organic solvents including benzene, ether, ethanol, acetone, chloroform and petroleum ether.
This substance is also steam‑distillable. It finds use in organic synthesis for dyestuffs and photographic film preservatives, and is widely applied as a preservative for pharmaceutical preparations.
Properties
Density | 1.37 |
Melting point | 63-65℃ |
Boiling point | 151° F (NTP, 1992) |
Refractive index | 1.5403 (73 C) |
Flash Point | 230° F (NTP, 1992) |
Vapour Pressure | 0.0±0.4 mmHg at 25°C |
Precise Quality | 142.018539 |
PSA | 20.23 |
logP | 2.354 |
Solubility | methanol: soluble1g/10 mL, clear, colorless |
AnalyticLaboratory Methods | Method: EPA-EAD 604; Procedure: gas chromatography with flame ionization detector/electron capture detector; Analyte: 3-methyl-4-chlorophenol;; Matrix: water;; Detection Level: 0.36 ug/L. |
Appearance | Off white crystals |
AutoIgnition | 590°C |
Storage | Ambient temperatures. |
Chemical Properties | white or pink crystals |
Physical Properties | Colorless, white, or pinkish crystals with a slight phenolic odor. On exposure to air it slowlybecomes light brown. |
Color/Form | White |
Contact Allergens | Chlorocresol is a biocide used for its disinfectant andpreservative properties, in topicals or cutting fluid. |
Decomposition | When heated to decomposition it emits toxic fumes of phosgene; /and hydrogen chloride;/. |
Odor | Said to be odorless when very pure, but usually a phenolic odor persists |
Odor Threshold | detection: 0.1 mg/kg |
PH | pH = 5.6 in saturated aqueous solution |
Physical | CHLOROCRESOL; is a pinkish to white crystalline solid with a phenolic odor. Melting point 64-66°C. Shipped as a solid or in a liquid carrier. Soluble in aqueous base. Toxic by ingestion, inhalation or skin absorption. Used as an external germicide. Used as a preservative in paints and inks. |
pKa | pKa 9.55(t = 25) (Uncertain) |
Water Solubility | 4 g/L (20 oC) |
Spectral Properties | Intense mass spectral peaks: 142 m/z (100%), 107 m/z (80%), 144 m/z (32%), 77 m/z (24%) |
MASS: 3931 (NIST/EPA/MSDC Mass Spectral Database, 1990 version); 1126 (Atlas of Mass Spectral Data, John Wiley and Sons, New York) | |
RAMAN: 224 (Sadtler Research Laboratories Spectral Collection) | |
IR: 5721 (Coblentz Society Spectral Collection) | |
UV: 1303 (Sadtler Research Laboratores Spectral Collection) | |
NMR: 10933(Sadtler Research Laboratories Spectral Collection); 236 (Johnson and Jankowski, Carbon-13 NMR Spectra, John Wiley and Sons, New York) | |
Stability | Stable. Incompatible with brass, oxidizing agents, copper, copper alloys. |
StorageTemp | Store below +30°C. |
Product Application of 4-Chloro-3-methylphenol CAS#59-50-7
4-Chloro-3-cresol belongs to phenolic compounds and serves for preservation and disinfection purposes.
It also acts as an activator targeting ryanodine receptors.
Furthermore, it finds application in organic synthesis for manufacturing dyes and film preservatives, and is widely adopted as a preservative for pharmaceutical preparations.
