D-Camphorsulfonic Acid CAS#3144-16-9
D-Camphorsulfonic Acid is a chiral organic sulfonic acid featuring a unique molecular structure and distinctive chemical properties. As an important intermediate in organic synthesis, it is widely utilized in pharmaceutical synthesis, asymmetric catalysis, and other advanced chemical applications.
Owing to its chiral characteristics, D-Camphorsulfonic Acid can serve as a chiral inducer in asymmetric reactions, facilitating the preparation of compounds with specific stereochemical configurations. Additionally, it exhibits acidic properties and can react with bases to form corresponding salts, further expanding its versatility in chemical processes.
(1S)-(+)-Camphor-10-sulphonic acid Chemical Properties
Product Name: | (1S)-(+)-Camphor-10-sulphonic acid |
Synonyms: | D-CAMPHORSULFONIC ACID;D(-)-CAMPHORSULPHONIC ACID;D-CAMPHORSULPHONIC ACID;CSA;D-REYCHLER'S ACID;D-OXO-10-BORNANESULFONIC ACID;(+)-BETA-CAMPHORSULFONIC ACID;(+)-CAMPHOR-10-SULFONIC ACID (BETA) |
CAS: | 3144-16-9 |
MF: | C10H16O4S |
MW: | 232.3 |
EINECS: | 221-554-1 |
Product Categories: | chiral;Pharmaceutical Intermediates;FINE Chemical & INTERMEDIATES;Chiral Compounds;Bicyclic Monoterpenes;Biochemistry;for Resolution of Bases;Optical Resolution;Reagents for Oligosaccharide Synthesis;Synthetic Organic Chemistry;Terpenes;Peptide;Sulfur & Selenium Compounds;3144-16-9;3597-91-9;11 |
Mol File: | 3144-16-9.mol |
Melting point | 196-200 °C (dec.)(lit.) |
alpha | 22 º (589nm, c=20, H2O 25 ºC) |
Boiling point | 344.46°C (rough estimate) |
density | 1.2981 (rough estimate) |
refractive index | 21.5 ° (C=5, H2O) |
storage temp. | Store below +30°C. |
solubility | Exhibit moderate solubility in HCCl. |
form | Crystalline Powder |
pka | 1.17±0.50(Predicted) |
color | White to off-white |
PH | 0.3 (200g/l, H2O) |
optical activity | [α]20/D +21.5±1°, c = 10% in H2O |
biological source | human |
Water Solubility | SOLUBLE |
Sensitive | Hygroscopic |
Merck | 141734 |
BRN | 2809675 |
Stability: | Stable. Protect from moisture. Incompatible with strong oxidizing agents, strong bases. |
InChIKey | MIOPJNTWMNEORI-GMSGAONNSA-N |
CAS DataBase Reference | 3144-16-9(CAS DataBase Reference) |
EPA Substance Registry System | Bicyclo[2.2.1]heptane-1-methanesulfonic acid, 7,7-dimethyl-2-oxo-, (1S,4R)- (3144-16-9) |
(1S)-(+)-Camphor-10-sulfonic acid is widely used as a stabilizing agent and an effective chiral resolving agent. Due to its excellent chiral recognition ability, it is commonly applied in the resolution of enantiomers and asymmetric synthesis processes.
It can also be used as a dopant in the template-free potentiostatic electropolymerization of chiral polyaniline (PANI) nanofibers, where (1S)-(+)-camphor-10-sulfonic acid (D-CSA) or (1R)-(-)-camphor-10-sulfonic acid (L-CSA) is introduced to induce chirality. In addition, it serves as an important raw material for the synthesis of quaternary ammonium compounds (QUATs) derived from (1S)-(+)-camphor-10-sulfonic acid.
