Products Description of 2-Piperazinone CAS#5625-67-2
2-Piperazinone is a nitrogen-bearing heterocyclic organic substance and a valuable aliphatic heterocyclic synthon for pharmaceutical development. It carries the molecular formula C₄H₈N₂O, alongside a molar mass of 100.12 and CAS registry number 5625-67-2.
This compound possesses a density of 1.1 ± 0.1 g/cm³, a melting range of 136–140°C, a boiling point of 307.1 ± 35.0°C at 760 mmHg, and a flash point of 166.3 ± 26.1°C. It manifests as a colourless solid under ambient temperature and finds its principal use in biochemical exploration.
2-Piperazinone Chemical Properties
| Melting point | 136-140 °C (lit.) |
| Boiling point | 164°C/5mmHg(lit.) |
| density | 1.053±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | Chloroform |
| form | Crystalline Powder |
| pka | 15.47±0.20(Predicted) |
| color | White to tan |
| Sensitive | Hygroscopic |
| Stability: | Stable, but may be light and moisture sensitive. Incompatible with oxidizing agents. |
| InChIKey | IWELDVXSEVIIGI-UHFFFAOYSA-N |
| CAS DataBase Reference | 5625-67-2(CAS DataBase Reference) |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38-43 |
| Safety Statements | 26-36/37 |
| RIDADR | 1759 |
| WGK Germany | 3 |
| HazardClass | 8 |
| PackingGroup | III |
| HS Code | 29349990 |
2-Piperazinone functions as a critical building block for organic synthesis and pharmaceutical manufacturing. It participates in the preparation of piperazine, norfloxacin, pipemidic acid and other quinolone compounds, as well as diverse drug intermediates targeting parasitic diseases, tuberculosis, diabetes and bacterial infections.
Furthermore, 2-Piperazinone acts as a starting material for an extensive array of end products. The list covers textile dyeing and finishing additives, rubber vulcanization promoters, anti-oxidants, biocides, stabilising agents, synthetic resins, man-made fibres and artificial leather.
