Product Description of 2-Dimethylaminoisopropyl Chloride Hydrochloride CAS#4584-49-0
2-Dimethylaminoisopropyl chloride hydrochloride is the hydrochloride form of 2-Dimethylaminoisopropyl Chloride, mainly used in the synthesis of lipophilic chalcone analogues with antitubercular activity.
2-Dimethylaminoisopropyl chloride hydrochloride Chemical Properties
| Melting point | 187-190 °C(lit.) |
| storage temp | Store below +30°C. |
| solubility | 2000g/l |
| form | Crystalline Powder |
| color | White to light cream |
| PH | 5-6 (500g/l, H2O, 20℃) |
| Water Solubility | 2000 g/L (20 º C) |
| Sensitive | Hygroscopic |
| BRN | 3670215 |
| InChI | InChI=1S/C5H12ClN.ClH/c1-5(6)4-7(2)3;/h5H,4H2,1-3H3;1H |
| InChIKey | OCWGRWAYARCRTQ-UHFFFAOYSA-N |
| SMILES | C(Cl)(C)CN(C)C.Cl |
| CAS DataBase Reference | 4584-49-0(CAS DataBase Reference) |
| EPA Substance Registry System | 2-Chloro-N,N-dimethyl-1-propanamine hydrochloride (4584-49-0) |
Safety Information
| Hazard Codes | Xn,Xi |
| Risk Statements | 22-36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | 2811 |
| WGK Germany | 3 |
| RTECS | TY1225000 |
| TSCA | Yes |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| HS Code | 29211980 |
Primary Applications
This compound is a key building block for several medications:
Antipsychotics: Synthesis of Chlorpromazine
Antihistamines: Synthesis of Promethazine (Phenergan) and Isothipendyl
Opioids: Intermediate for Methadone production
Antidepressants: Synthesis of Doxepin hydrochloride
Other: Used in the creation of methaqualone and lipophilic chalcones for antitubercular research
