Terephthalaldehyde CAS#623-27-8

Critical Fine Chemical Building Block: Terephthalaldehyde is a major derivative from p-xylene and occupies an indispensable position as a feedstock within fine chemical manufacturing.

High Polymerization Activity: Equipped with two reactive aldehyde functional groups, it is capable of homopolymerization or copolymerization reactions to construct a broad range of polymeric materials.

Diversified Material Scenarios: It finds extensive utilization for the fabrication of fluorescent substances, catalyst supports and other high-value polymer products with superior performance.

Mature Industrial Synthesis Routes: Reliable commercial production can be realized via the chlorination of p-xylene and subsequent hydrolysis, which guarantees steady and consistent bulk supply.

Product Description of Terephthalaldehyde CAS#623-27-8

Terephthalaldehyde is an important fine chemical intermediate derived from paraxylene. Its molecular structure contains two active aldehyde groups, enabling it to undergo self-polymerization or copolymerization with other monomers to produce a variety of polymer materials. These polymers are widely used in the synthesis of fluorescent materials, catalyst carriers, and other high-performance macromolecular products.

Traditionally, terephthalaldehyde is produced through the chlorination of p-xylene followed by hydrolysis in the presence of nitric acid or metal oxide catalysts.1774402551677776.jpg.webp

Terephthalaldehyde Chemical Properties

Melting point 114-116 °C (lit.)
Boiling point 245-248 °C (lit.)
Density 1,06 g/cm3
Vapor pressure 0.25-0.46Pa at 20-25℃
Refractive index 1.4800 (estimate)
Fp 76 °C
Storage tempStore below +30°C.
Solubility 3g/l
Form Crystalline Powder
Color White to light yellow
Water Solubility 3 g/L (50 ºC)
Sensitive Air Sensitive
BRN 385863
InChIKeyKUCOHFSKRZZVRO-UHFFFAOYSA-N
LogP1 at 20.1℃ and pH6.6-6.8
CAS DataBase Reference623-27-8(CAS DataBase Reference)
NIST Chemistry Reference1,4-Benzenedicarboxaldehyde(623-27-8)
EPA Substance Registry System1,4-Benzenedicarboxaldehyde (623-27-8)
Hazard Codes Xi
Risk Statements 36/37/38-36/37
Safety Statements 22-24/25-36-26-37/39
WGK Germany 1
RTECS WZ0430000
Hazard Note Irritant
TSCA Yes
HS Code 29122900
Hazardous Substances Data623-27-8(Hazardous Substances Data)

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Product Application of Terephthalaldehyde CAS#623‑27‑8 Terephthalaldehyde serves as a primary raw material for whitening agents, poly(methylstyrene‑co‑indene), plastic goods and pesticide formulations. It also participates in building diverse organic‑molecule frameworks, including synthetic intermediates such as bromocyclopentane.

Moreover, it supports the manufacturing of solid iodophor disinfectants. In these systems, surfactants act as carriers to generate iodine‑containing coordination complexes. Such disinfectant products deliver broad‑spectrum, high‑efficiency bactericidal performance coupled with favorable stability and safe operating profiles. They are suitable for preoperative skin antisepsis as well as sanitary treatment for oral cavities, intestinal tracts, urethral and cervical mucosal tissues.1774402588616820.jpg.webp

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