2-Bromo-2-nitro-1,3-propanediol CAS#52-51-7

Favorable Solubility across Various Solvents: It dissolves easily in water, ethanol, propylene glycol and ethyl acetate, allowing it to adapt well to different formulation systems.

Moderate Thermal Stability: The compound possesses a clear melting point range of 122–130°C, which demonstrates steady physical attributes.

Low Solubility in Oils and Select Organic Solvents: It shows slight solubility in oils and poor solubility in chloroform, acetone and comparable solvents, helping achieve controllable application performance.

Strong Formulation Adaptability: Its balanced solubility characteristics render it appropriate for antibacterial preparations and other associated chemical formulations.

Product Description of Lopol (2‑Bromo‑2‑nitro‑1,3‑propanediol)

Lopol, with the chemical name 2‑bromo‑2‑nitro‑1,3‑propanediol, is also called bromonitrol or antibacterial alcohol. It takes the form of white crystalline powder and has a melting point ranging from 122–130°C.

It dissolves freely in water, ethanol, propylene glycol and ethyl acetate, shows slight solubility in oils, and is poorly soluble in chloroform, acetone and other similar solvents.

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Properties

Density

1.91

Melting point

124-129℃

Boiling point

358 °C at 760 mmHg

Refractive index

1.574

Flash Point

170.3 °C

Vapour Pressure

0.0±1.8 mmHg at 25°C

Precise Quality

198.948

PSA

86.28

logP

-0.1379

Solubility

H2O: soluble100mg/mL, clear, colorless to faintly yellow

Appearance

White to slightly yellow crystals or crystalline powder

Storage

Ambient temperatures.

Chemical Properties

off-white crystalline powder

Physical Properties

Colorless, white, or pinkish crystals with a slight phenolic odor. On exposure to air it slowlybecomes light brown.

Color/Form

White to yellow

Contact Allergens

Bronopol is a preservative sometimes considered as aformaldehyde releaser. It was reported to be an allergenin cosmetics, cleaning agents, dairy workers, and alubricant jelly used for ultrasound examination.

Decomposition

The substance decomposes on heating or on burning producing toxic and corrosive fumes, including hydrogen bromide and nitrogen oxides.

Odor

Odorless

pKa

12.02±0.10(Predicted)

Water Solubility

25 g/100 mL (22 oC)

Spectral Properties

MASS: 75372 (NIST/EPA/MSDC Mass Spectral Database, 1990 version); 1023 Wiley

Stability

Stable. Hygroscopic. Incompatible with strong oxidizing agents, strong bases, strong reducing agents, acid chlorides and anhydrides, moisture.

StorageTemp

Inert atmosphere,Room Temperature

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Product Application of Bropol

Bropol delivers potent inhibitory effects against a wide array of phytopathogenic bacteria and is primarily deployed as a seed treatment agent.

Thanks to its broad‑spectrum antibacterial traits, it has served as a disinfectant within the pharmaceutical sector since the 1960s. As the cosmetics industry expanded rapidly, its favorable water solubility and robust antimicrobial potency also facilitated its extensive adoption as a preservative in cosmetic products.

In recent years, Bropol has found rising utilization in feed additives, coating systems, fur preservation, circulating water disinfection for air conditioning units, sterilization of oilfield injection water, as well as sanitation treatment for aircraft, vehicles and vessels, driving sustained growth in market demand.

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