4-Amino-N-methylbenzamide is a specialty chemical with CAS number 6274-22-2, molecular formula C8H10N2O, and molecular weight 150.18. It has a density of 1.137 g/cm³, a melting point of 181°C, a boiling point of 364.1±25.0°C (760 mmHg), a flash point of 174.0±23.2°C, and a vapor pressure of 1.72E-05 mmHg at 25°C. It appears as white crystals, is soluble in methanol, and must be stored in a sealed container at room temperature. Its molecular structural parameters include a molar refractive index of 44.11, a molar volume of 132.0 m³/mol, and a polarizability of 17.48 × 10⁻²⁴ cm³.
4-Amino-N-methylbenzamide Chemical Properties
| Melting point | 181 °C |
| Boiling point | 364.1±25.0 °C(Predicted) |
| Density | 1.137 |
| Storage temp | Keep in dark place,Inert atmosphere,Room temperature |
| Solubility | soluble in Methanol |
| Form | powder to crystal |
| Pka | 15.84±0.46(Predicted) |
| Color | White to Light yellow to Light orange |
| CAS DataBase Reference | 6274-22-2(CAS DataBase Reference) |
| Hazard Codes | Xi |
| HazardClass | IRRITANT |
| HS Code | 29242990 |
Applications
Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), including compounds related to kinase inhibitors like Defactinib.
Organic Synthesis: Serves as a building block for creating complex nitrogen-containing organic molecules.
