Product Description of 4‑Morpholineethanesulfonic Acid CAS#4432‑31‑9
At ambient temperature and standard atmospheric pressure, 4‑Morpholineethanesulfonic Acid exists as a white solid. This compound dissolves easily in polar solvents such as water, ethanol, methanol and acetone, yet shows no solubility in non‑polar solvents.
Its molecular architecture consists of a morpholine ring together with an ethanesulfonic acid functional group. As a nitrogen‑bearing heterocyclic unit, the morpholine ring endows the substance with outstanding chemical stability and inertness, alongside negligible toxicity and minimal biological irritation.
On the other hand, the negatively‑charged ethanesulfonic acid moiety delivers favourable aqueous solubility and robust buffering performance. These properties render the compound well‑adapted for biochemical research, pharmaceutical manufacturing and laboratory‑related usage scenarios.
4-Morpholineethanesulfonic acid Chemical Properties
| Melting point | >300 °C(lit.) |
| Boiling point | 102°C |
| Density | 1.208 (estimate) |
| Refractive index | 1.5500 (estimate) |
| Storage temp. | 2-8°C |
| Solubility | H2O: 0.5 M at 20 °C, clear |
| Form | Powder |
| Pka | pKa at 0.1M ionic: 0°, 6.38; 20°, 6.15; 37°, 5.98; pKa1 1.99; pKa2 6.21; pKa/°C -0.011 |
| Color | White |
| PH | 2.5-4.0 (25℃ in neat) |
| PH Range | 5.5 - 6.7 |
| Water Solubility | 185.2g/L at 20℃ |
| λmax | λ: 260 nm Amax: 0.01 |
| λ: 280 nm Amax: 0.01 | |
| Merck | 135929 |
| BRN | 6350956 |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| InChIKey | SXGZJKUKBWWHRA-UHFFFAOYSA-N |
| LogP | -2.2 at 20℃ |
| CAS DataBase Reference | 4432-31-9(CAS DataBase Reference) |
| EPA Substance Registry System | 4-Morpholineethanesulfonic acid (4432-31-9) |
Safety Information
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36-24/25-22 |
| WGK Germany | 1 |
| RTECS | QE9104530 |
| HS Code | 29349990 |
Product Application of 4‑Morpholineethanesulfonic Acid CAS#4432‑31‑9
This compound finds broad‑ranging application as a calcium‑soap dispersant within bar‑soap and toilet‑soap formulations. In detergent systems, it acts as an efficient low‑phosphorus or phosphorus‑free substitute for https://www.whchemicalsd.com/catalysts/sodium.html. Furthermore, it can be incorporated as an active component inside liquid cleaning preparations.
For industrial‑grade scenarios, it works as a moderate‑foam mineral flotation reagent. Additionally, it delivers favorable performance as dispersant and wetting agent for leather degreasing operations, dyestuffs, https://www.whchemicalsd.com/dyestuffs-and/, as well as pesticide formulations.
Beyond the above uses, the chemical serves as a deinking agent for the printing sector. It helps boost ink‑stripping efficiency throughout paper recycling and processing workflows.


