Product Description of Chlorhexidine CAS#55‑56‑1
Chlorhexidine is extensively adopted for the prophylaxis and intervention of diverse oral infections, such as gingivitis including acute necrotizing ulcerative gingivitis, oral complications following dental operations, and oral infectious conditions occurring in cancer and leukemia patients. It is also indicated for stomatitis and follicular stomatitis induced by bacterial or fungal pathogens, including cases related to denture use.
Furthermore, Chlorhexidine contributes to the suppression of dental plaque accumulation. It can act as a disinfecting agent for medical devices and skin, and serve as a preservative component incorporated into eye drop preparations.
Product Parameters of Chlorhexidine CAS#55-56-1
Name | Chlorhexidine |
CAS | No.55-56-1 |
CID | 9552079 |
EINECS(EC#) | 223-026-6; 200-238-7; 200-302-4 |
Molecular Formula | C22H30Cl2N10 (isomer) |
Inchi | InChI=1S/C22H30Cl2N10/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18/h5-12H,1-4,13-14H2,(H5,25,27,29,31,33)(H5,26,28,30,32,34) |
InChIkey | GHXZTYHSJHQHIJ-UHFFFAOYSA-N |
Canonical Smiles | C1=CC(=CC=C1NC(=NC(=NCCCCCCN=C(N)N=C(N)NC2=CC=C(C=C2)Cl)N)N)Cl |
Isomers Smiles | C1=CC(=CC=C1N/C(=N/C(=NCCCCCCN=C(/N=C(/NC2=CC=C(C=C2)Cl)\N)N)N)/N)Cl |
Density | 1.1555 (rough estimate) |
Melting point | 134-136 °C(lit.) |
Boiling point | 641.45°C (rough estimate) |
Refractive index | 1.6300 (estimate) |
Flash Point | 376.7°C |
Vapour Pressure | 0.0±1.7 mmHg at 25°C |
Precise Quality | 564.224 |
PSA | 204.88 |
logP | 6.3747 |
Solubility | 0.08 g/100 mL (20 oC) |
Appearance | white powder |
Chemical Properties | Chlorhexidine occurs as an odorless, bitter tasting, white crystallinepowder. |
Color/Form | Crystals from methanol Solid |
pKa | pKa 10.78 (Uncertain) |
Water Solubility | 0.08 g/100 mL (20 oC) |
Stability | Stable. Incompatible with strong oxidizing agents. |
StorageTemp | Keep tightly closed. |
Product Application of Chlorhexidine CAS#55‑56‑1
Chlorhexidine is extensively employed for the prevention and management of gingivitis (acute necrotizing ulcerative gingivitis included), post‑dental‑surgery oral infections, and oral infectious disorders among cancer and leukemia patients. It is also utilized to remedy stomatitis and follicular stomatitis triggered by bacterial or fungal oral infections linked to denture wearing. Moreover, it assists in lowering dental plaque formation and can function as a disinfectant for apparatus and skin, alongside a preservative additive for eye drop preparations.
As a surfactant‑based antimicrobial substance, Chlorhexidine possesses potent broad‑spectrum antibacterial and bactericidal properties. It demonstrates efficacy against both Gram‑positive and Gram‑negative bacteria, which qualifies it for a wide array of disinfection and antimicrobial scenarios.
