Products Description of Alpha‑Arbutin (CAS No. 84380‑01‑8)
Arbutin is a naturally occurring substance isolated from botanical sources including bearberry, cranberry and mulberry. Its functional mechanism lies in blocking the generation of melanin, the pigment that governs skin colouration.
Alpha‑Arbutin represents a synthetic stereoisomer of this plant‑origin ingredient and features superior structural stability. It is widely adopted as a topical brightening raw material to fade sun‑induced pigment patches, hyperpigmentation, and acne scars triggered by ultraviolet exposure and inflammatory breakouts.
Besides its whitening efficacy, Alpha‑Arbutin carries antioxidant properties that defend skin against harm induced by environmental stress and UV radiation.
Frequently compounded together with retinol, it is a mainstream active additive for anti‑aging skincare formulas. It helps reduce the visual prominence of age pigment, fine creases and wrinkles, bringing about a smoother and more youthful skin appearance.
| Product Name: | alpha-Arbutin |
| Synonyms: | Alpha Arbutin Powder;4-hydroquinone-alpha-d-glucopyranoside;alpha-arbutin;a-Arbutin;Hydroquinone O-α-D-Glucopyranoside;4-Hydroxyphenyl a-D-glucopyranoside;(2R,3S,4S,5R,6S)-2-(HYDROXYMETHYL)-6-(4-HYDROXYPHENOXY)TETRAHYDROPYRAN-3,4,5-TRIOL;4-hydroxyphenyl alpha-D-glucopyranoside |
| CAS: | 84380-01-8 |
| MF: | C12H16O7 |
| MW: | 272.25 |
| EINECS: | 209-795-0 |
| Product Categories: | Plant extract;Aromatics;Carbohydrates & Derivatives;Intermediates & Fine Chemicals;Pharmaceuticals;84380-01-8 |
| Mol File: | 84380-01-8.mol |
Alpha-Arbutin Chemical Properties
| Melting point | 195-196°C |
| Boiling point | 561.6±50.0 °C(Predicted) |
| Density | 1.556±0.06 g/cm3(Predicted) |
| Storage temp. | 2-8°C |
| Solubility | DMSO (Slightly), Methanol (Slightly) |
| Form | Solid |
| Pka | 10.10±0.15(Predicted) |
| Color | White to Off-White |
| BRN | 89675 |
| InChI | InChI=1/C12H16O7/c13-5-8-9(15)10(16)11(17)12(19-8)18-7-3-1-6(14)2-4-7/h1-4,8-17H,5H2/t8-,9-,10+,11-,12+/s3 |
| InChIKey | BJRNKVDFDLYUGJ-ZIQFBCGOSA-N |
| SMILES | O(C1C=CC(O)=CC=1)[C@@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O |&1:8,9,10,12,14,r| |
| CAS DataBase Reference | 84380-01-8(CAS DataBase Reference) |
Product Usage
α‑Arbutin (CAS No. 84380‑01‑8) finds its major application within cosmetic manufacturing. It delivers powerful effects by suppressing tyrosinase activity and interrupting melanin generation. This active substance is regularly added to whitening lotions, serums, facial masks and other skincare blends to lighten skin tone and diminish dark pigmented spots.
Within medical research, α‑arbutin shows promising therapeutic potential for managing pigmentary disorders including melasma.
Additionally, thanks to its antioxidant traits, it is a popular choice during skincare formulation development. It safeguards skin cells against oxidative injury from free radicals and helps maintain healthy skin conditions.
